Arrayed CRISPR gRNA Libraries
CRISPR通路文库
利用我们的多向导技术和高质量sgRNA的排列式格式，可在整个CRISPR筛选中可靠地实现高效的基因敲除。
凭借无与伦比的快速交付，目标的识别和验证从未如此迅速。
借助我们的CRISPR通路文库，改变您的目标发现
我们提供30多种通路文库，包括可药物靶点、GPCRs、激酶和免疫肿瘤学靶点等。这些文库非常适合目标识别研究，提供了一个全面的基因集，可帮助您开始发现过程。部分通路文库可在一周内快速发货，让您尽早开始筛选。我们的通路文库采用独特的多向导策略，可实现可预测的高效敲除，降低假阴性。请参阅下表，获取可用通路文库的完整列表 - 联系我们进行订购。如果您对更广泛的覆盖感兴趣，请查看我们的全基因组文库。如果您对特定的目标集感兴趣，请查看我们的CRISPR用户自定义文库。
CRISPR通路文库列表与基因数
Apoptosis Pathway Library: 1997
Autophagy Library: 460
B-Cell Activation Pathway Library: 242
Cell Adhesion Genes Library: 1479
Cell Cycle Regulators Library: 1251
Cell Surface Proteins Library: 2738
Complete Druggable Library: 8478
Kinase Library: 1035
Cytokines and Chemokines Library: 310
Cytoskeleton Genes Library: 1745
Deubiquitinating Enzymes Library: 117
DNA Repair Pathway Library: 530
Epigenetic Regulators Library: 826
Essential Genes Library: 2553
Extracellular Matrix Genes Library: 363
G-Protein Coupled Receptors Library: 1046
Helicases Library: 154
Immunology/Immuno-Oncology Library: 3098
Ion Channels Library: 685
JAK-STAT Pathway Library: 194
Metabolic Activity Library: 11432
Nuclear Hormone Receptors Library: 192
p53 Pathway Library: 319
Pattern Recognition Receptors and Signaling Pathways Library: 303
Phosphatases Library: 344
SARS-CoV-2 Druggable Interactome Library: 63
SARS-CoV-2 Interactome Library: 324
Secreted Proteins Library: 5292
Serine Proteases Library: 263
T-Cell Activation Pathway Library: 524
Transcription Factors Library: 2358
Tumor Suppressors Library: 1055
Tyrosine Kinases Library: 152
Ubiquitin Ligases Activity (E1, E2, E3) Library: 1159
Ubiquitin Protein Ligases Library: 336
产品种类
物种
- 人类
规格
- 人类 - 150 pmol 至 1500 pmol
Plate Format
- 人类 96孔板：Nunc深孔板
- 人类 384孔板：Nunc深孔板，ECHO®，或ECHO® LDV
交付内容
- Multi-guide plated library (up to 3 guides per well), dry
- sgRNAs are modified (2' O-Methyl analog on first and last 3 bases; 3' phosphorothioate between first 3 and last 2 bases)
- Modifications help resist degradation and prevent triggering intracellular immune responses
- SpCas9 proprietary EZ Scaffold
- Library plate layouts (.csv)
- Multi-guide sgRNA sequences provided for each gene target
- 联系我们
如果您有任何关于CRISPR的问题，都欢迎与我们交流，期待您的留言！
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